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. Author manuscript; available in PMC: 2015 Aug 24.
Published in final edited form as: J Hypertens. 2015 Aug;33(8):1602–1610. doi: 10.1097/HJH.0000000000000591

Figure 3.

Figure 3

Effect of MBG (100 nmol/L), canrenone (CAN)(10 umol/L) and their combination on responsiveness of rat aortic rings to 100 nmol/L endothelin-1 (Et-1) (a), and on sodium nitroprusside-induced vasorelaxation following contraction induced by 100 nmol/L Et-1, representative recordings (b). Concentration-response curves determined 5–8 times and averaged to give means ± SEM for EC50 (c). By repeated measures ANOVA and Bonferroni test: control (CTRL) vs. MBG – P<0.01; MBG+CAN vs. MBG – P<0.01.