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. Author manuscript; available in PMC: 2015 Aug 24.
Published in final edited form as: Curr Protoc Protein Sci. 2010 Apr;0 7:Unit–7.13. doi: 10.1002/0471140864.ps0713s60

Figure 7.13.6.

Figure 7.13.6

Meniscus fit from RMSD values obtained in multiple iterations of 2DSA analysis fits. Such iterations always result in well-conditioned error surfaces that are easily fit by second-or third-order polynomials as shown here. The minimum occurs at the position where the first derivative of the polynomial is equal to zero.