Table 3.
Mutant P53, BCL-2 and BAX expression levels comparison (χ̄±s).
| Groups | N | Mutant P53 (pg·mL−1) | BCL-2 (pg·mL−1) | BAX (pg·mL−1) | BCL-2/BAX |
|---|---|---|---|---|---|
| Negative control | 6 | 245.4±4.37*,& | 93.0±2.8*,& | 85.4±1.3 | 123.3%*,& |
| Cnidium lactone 280 mg/Kg group | 5 | 156.5±6.38*,# | 54.0±2.4*,# | 69.8±4.1 | 78.3%*,# |
| Cnidium lactone 140 mg/Kg group | 6 | 179.5±5.26*,# | 60.2±2.2*,# | 71.0±3.2 | 84.5%*,# |
| Cnidium lactone 70 mg/Kg group | 6 | 193.8±6.51* | 69.7±1.5* | 73.2±3.6 | 95.2%* |
| Cyclophosphamide group | 5 | 192.0±5.72#,& | 75.4±1.6#,& | 74.0±2.8 | 101.3%#,& |
*
P<0.01, compared with control;
#
P<0.05, compared with cyclophosphamide group;
&
P<0.05, compared with control.