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. Author manuscript; available in PMC: 2015 Aug 24.
Published in final edited form as: Pediatrics. 2012 Dec 17;131(1):e27–e36. doi: 10.1542/peds.2012-1616

TABLE 3.

Survival Probabilities for Infants With DS by Selected Maternal and Child Characteristics in 10 US Regions During 1983–2003

Births <28 d
1 y
5 y
10 y
20 y
Deaths Survival, % (95% CI) Deaths Survival, % (95% CI) Deaths Survival, % (95% CI) Deaths Survival, % (95% CI) Deaths Survival, % (95% CI)
Maternal education (y)
 ≥12 11437 220 98.1 (97.8–98.3) 787 93.1 (92.7–93.6) 995 91.1 (90.5–91.6) 1035 90.3 (89.7–90.9) 404 88.9 (87.9–89.8)
 <12 4132 66 98.4 (98.0–98.7) 309 92.6 (91.7–93.3) 381 90.4 (89.4–91.9) 399 89.3 (88.3–90.3) 1056 86.0 (81.3–89.6)
 Missing 937 32 84 113 117 124
Plurality
 Singleton 16048 308 98.1 (97.9–98.3) 1129 93.0 (92.6–93.4)a 1425 90.8 (90.4–91.3)a 1486 90.1 (89.6–90.5)a 1518 88.2 (87.2–89.1)a
 Multiple 440 10 97.7 (95.8–98.8) 50 88.6 (85.3–91.2)a 61 86.0 (82.3–88.9)a 62 85.5 (81.8–88.6)a 63 84.4 (79.9–88.0)a
 Missing 18 0 1 3 3 3
CHDs
 No 8576 176 97.9 (97.6–98.2) 343 96.0 (95.5–96.4)b 417 95.0 (94.5–95.5)b 444 94.4 (93.8–94.9)b 460 93.0 (92.0–93.9)b
 Yes 7930 142 98.2 (97.9–98.5) 837 89.6 (88.9–90.2)b 1072 86.0 (85.2–86.7)b 1107 85.0 (84.1–85.8)b 1124 82.2 (80.1–84.1)b
 Missing 0
Birth cohort
 1983–1989 2454 51 97.9 (97.2–98.4) 213 91.3 (90.0–92.4)b 292 88.1 (86.8–89.3)b 310 87.4 (86.0–88.6)b 334 85.7 (84.1–87.1)b
 1990–1996 5441 109 98.0 (97.6–98.3) 477 91.2 (90.5–92.0)b 589 89.2 (88.3–90.0)b 624 88.4 (87.6–89.3)b
 1997–2003 8611 158 98.2 (97.9–98.4) 490 94.3 (93.8–94.8)b 608 92.5 (91.9–93.0)b

—, no estimates were produced because of small numbers.

a

P < .001.

b

P < .0001.