TABLE 4.
aHRsa for Select Covariates Among Children With Down Syndrome (n = 16 418) by Age at Follow-up From 10 US Regions, 1983–2003
| 1 mo | 2–12 mo | 1–5 y | 6–10 y | 11–20 y | Overall | |
|---|---|---|---|---|---|---|
| Race/ethnicity | ||||||
| White | Referent | Referent | Referent | Referent | Referent | Referent |
| Blacks | 1.0 (0.7–1.5) | 1.4 (1.2–1.8)b | 1.9 (1.4–2.6)b | 2.0 (1.0–4.0)b | 1.7 (0.6–5.1) | 1.4 (1.0–1.6) |
| Hispanics | 0.8 (0.6–1.0)b | 1.0 (0.9–1.2) | 0.8 (0.6–1.0) | 0.6 (0.3–1.2) | 1.7 (0.6–4.7) | 0.8 (0.7–0.9)b |
| Other | 1.3 (0.8–2.0) | 1.3 (1.0–1.7) | 1.2 (0.8–2.0) | 2.4 (1.1–5.4)b | 1.9 (0.4–8.0) | 1.3 (1.1–1.6)b |
| Birth wt | ||||||
| ≥2500 | Referent | Referent | Referent | Referent | Referent | Referent |
| 1500–2499 | 2.4 (1.8–3.2)b | 1.9 (1.7–2.3)b | 1.4 (1.1–1.9)b | 1.2 (0.7–2.4) | 1.3 (0.5–3.1) | 1.8 (1.6–2.0)b |
| <1500 | 23.8 (18.4–30.7)b | 6.9 (5.6–8.6)b | 2.1 (1.2–3.9)b | 1.1 (0.2–8.2) | 8.5 (2.5–28.6)b | 8.5 (7.3–9.8)b |
| Maternal age | ||||||
| <35 | Referent | Referent | Referent | Referent | Referent | Referent |
| ≥35 y | 1.0 (1.0–1.0) | 1.0 (1.0–1.0) | 1.0 (1.0–1.0) | 1.0 (1.0–1.0) | 1.0 (0.9–1.0) | 1.0 (1.0–1.0) |
| CHD, yes vs no (referent) | 0.8 (0.6–1.2) | 4.6 (3.9–5.4)b | 4.0 (3.1–5.2)b | 1.9 (1.1–3.2)b | 2.0 (1.0–4.0)b | 2.7 (2.4–3.0)b |
| Birth cohort | ||||||
| 1983–1989 | Referent | Referent | Referent | |||
| 1990–1996 | 0.9 (0.6–1.2) | 1.0 (0.8–1.2) | 0.6 (0.5–0.8)b | — | — | — |
| 1997–2003 | 0.8 (0.5–1.1) | 0.5 (0.4–0.6)b | 0.5 (0.4–0.7)b | — | — | — |
Birth wt reference group is ≥2500. Survival probability among non-Hispanic blacks, Hispanic, and other was compared with the survival probability among non-Hispanic whites. —, no estimates were produced because of small numbers.
a
Adjusted for race/ethnicity, birth wt, maternal age and education, presence of a CHD, birth period, and region of birth.
b
Statistical difference in survival probabilities between category stratum and the referent group.