Table 1.

Characteristics of the study population of 20 surviving ALD patients with testing for adrenal insufficiency 1 - 7 years post transplantation

Variable	Adrenal function (pre-HCT/post-HCT)
	abnormal/abnormal	normal/abnormal	normal/normal
N	16	3	1
Age at HCT (years), mean±s.d.	7.9±2.3	10.1±0.2	8.3
Years between HCT and ACTH stimulation test mean±s.d. (range)	2.5±2.1 (1 - 7)	1.6±0.6 (1 - 2)	4 (NA)
Peak stimulated cortisol level (mg/dL) post HCT mean±s.d.	4.0±5.3	12.4±3.4	21.2
Currently on hydrocortisone (N, %)	16 (100%)	3 (100%)	0 (0%)
Currently on fludrocortisone (N, %)	9 (56%)	3 (100%)	0 (0%)
Donor type (N)
Cord blood	7	2	0
Related marrow	7	1	1
Unrelated marrow	2	0	0
Conditioning (N)
Myeloablative	12	2	0
Non-myeloablative	4	1	1

Abbreviations: ACTH=adrenocorticotropic hormone; ALD=adrenoleukodystrophy; HCT=hematopoietic cell transplantation; NA=not available.