Table 1.

OCT, LF, ICDAS-II, and radiograph assessment of all teeth versus Histopathology (gold standard)

	Before sealant applied				After sealant applied
All teeth (n=120)	OCT* %	LF %	ICDAS %	Radiograph %	OCT %	LF %
PPV†	91.3	93.2	91.1	86.9	98.6	68.8
NPV	89.5	65.6	85.4	54.4	83.3	50.0
Sensitivity	94.0	65.2	92.3	67.1	89.9	95.1
Specificity	85.0	97.6	83.3	79.5	97.6	10.3
False Positives (n)	6	1	7	8	1	35
False Negatives (n)	4	21	6	26	8	4
Group 1 (sealed with Clear Vue) (n=60)
PPV	96.8	100.0	87.2	83.9	100.0	72.2
NPV	90.5	58.8	71.4	53.6	80.0	50.0
Sensitivity	93.8	65.0	85.0	66.7	87.5	92.9
Specificity	95.0	100	75.0	75.0	100.0	16.7
False Positives (n)	1	0	5	5	0	15
False Negatives (n)	2	14	6	13	5	3
Group 2 (sealed with Helioseal) (n=60)
PPV	88.1	97.0	95.0	90.0	97.3	65.5
NPV	88.9	74.1	100.0	55.2	87.0	50.0
Sensitivity	94.9	82.1	100.0	67.5	92.3	97.4
Specificity	76.2	95.2	90.0	84.2	95.2	4.8
False Positives (n)	5	1	2	3	1	20
False Negatives (n)	2	7	0	13	3	1

^*Optical Coherence Tomography (OCT), Laser Fluorescence (LF), International Caries Detection and Assessment System (ICDAS-II)

^†PPV = Positive Predictive Value; NPV = Negative Predictive Value