Table 2.
Cardiopulmonary exercise test results in 83 patients with sarcoidosis classified according to radiological stage of the disease
| Maximal exercise data | All (n=83) | Stage
|
P-value
|
||||
|---|---|---|---|---|---|---|---|
| I (n=43) | II–III (n=31) | IV (n=9) | I vs II–III | I vs IV | II–III vs IV | ||
| Workload, W | 97.570±53.630 | 106.200±55.320 | 90.030±52.560 | 82.330±46.600 | 0.135 | 0.176 | 0.869 |
| VO2 peak, %pred | 84.600±15.310 | 88.280±14.360 | 82.650±15.120 | 73.780±15.560 | 0.166 | 0.003 | 0.365 |
| VO2 peak, mL/kg/min | 20.620±5.661 | 21.960±5.210 | 19.550±6.240 | 17.960±4.250 | 0.098 | 0.068 | 0.596 |
| ΔVO2/ΔWR, mL/W | 2.590±14.620 | 20.130±17.030 | 21.210±12.330 | 20.620±9.725 | 0.174 | 0.358 | 0.795 |
| VE, L/min | 56.420±20.220 | 58.280±21.910 | 54.320±19.570 | 54.780±13.960 | 0.232 | 0.952 | 0.609 |
| VE/VO2, VT | 23.800±4.190 | 23.020±3.650 | 23.770±3.970 | 24.640±4.270 | 0.345 | 0.134 | 0.367 |
| VE/VCO2, VT | 26.450±4.660 | 25.580±4.050 | 26.410±4.410 | 30.730±6.260 | 0.232 | <0.001 | 0.006 |
| BF max, min−1 | 39.200±12.000 | 35.700±10.000 | 37.800±11.000 | 42.900±10.000 | 0.356 | 0.561 | 0.563 |
| VT peak, FVC% | 52.300±25.000 | 51.340±32.000 | 51.200±45.000 | 54.010±56.000 | 0.508 | 0.163 | 0.124 |
| HR peak | 145.200±23.400 | 149.500±22.660 | 138.900±24.790 | 146.400±18.900 | 0.078 | 0.283 | 0.909 |
| AT | 16.110±18.500 | 18.620±25.220 | 13.630±4.820 | 12.620±3.310 | 0.245 | 0.296 | 0.687 |
| Oxygen pulse peak | 11.060±4.100 | 11.290±4.040 | 11.240±4.510 | 9.360±2.560 | 0.726 | 0.316 | 0.236 |
| ΔHR/ΔVO2 | 68.830±24.000 | 71.430±25.000 | 65.500±23.000 | 74.670±27.000 | 0.063 | 0.639 | 0.245 |
Note: Results are expressed as mean ± standard deviation.
Abbreviations: FVC%, percent forced vital capacity; %pred, percent predicted; AT, anaerobic threshold; BF, breathing frequency; HR, heart rate; VE, minute ventilation; VCO2, carbon dioxide production; VO2, oxygen consumption; VT, tidal volume; VT, ventilatory threshold; WR, workload.