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. 2015 Aug 24;10(8):e0135918. doi: 10.1371/journal.pone.0135918

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© 2015 Wang et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 9 — Expected values of the test statistic under different MAFs in controls, ORs, and case-to-control ratios based on one single SNP. (A) Case-to-control ratio is 1:1 (1000:1000). (B) 1:1.5 (1000:1500). (C) 1.5:1 (1500:1000). Red solid line for protective SNPs with OR = 0.5, red dashed line for OR = 0.8, blue solid line for OR = 2, and blue dashed line for OR = 1.25.