Table 4. Clinical characteristics of subjects classified with CAD in the RA, IBD and DM cohorts (PPV of CAD classification > = 90% PPV*).
| Clinical characteristics | RA, n = 4453 | IBD, n = 10,974 | DM, n = 65,099 | |||
|---|---|---|---|---|---|---|
| CAD yes, n = 245 (5.0%) | CAD no, n = 4208 | CAD yes, n = 457 (4.2%) | CAD no, n = 10,517 | CAD yes, n = 16,962 (26.1%) | CAD no, n = 48,136 | |
| Mean age, (SD) | 72.9 (10.1) | 60.2 (14.7) | 71.3 (11.0) | 46.3 (18.4) | 71.7 (11.1) | 62.1 (15.9) |
| Male gender (%) | 45.7 | 19.4 | 70.7 | 45.7 | 66.9 | 48.3 |
| Race (%) | ||||||
| White | 80.0 | 66.1 | 93.0 | 85.0 | 78.7 | 63.7 |
| Black | 7.4 | 5.6 | 2.2 | 3.0 | 7.1 | 14.0 |
| Comorbidity | ||||||
| Hypertension (%) | 88.2 | 35.5 | 85.6 | 23.1 | 92.2 | 75.4 |
| Diabetes mellitus (%) | 40.0 | 12.2 | 35.2 | 7.1 | N/A | N/A |
| Hyperlipidemia | 82.5 | 26.0 | 81.0 | 20.6 | 83.6 | 61.5 |
| Smoking status, ever vs never (%) | 66.9 | 30.1 | 75.7 | 33.2 | 68.8 | 45.9 |
| Follow-up (months), mean (SD) | 139.7 (58.5) | 101.2 (65.5) | 112.9 (75.0) | 83.7 (68.1) | 98.1 (69.6) | 96.7 (71.0) |
*Selected specificity cutoff for each cohort based on PPV> = 90%; RA based on medical record review.