Table 6. Differences of estradiol, CTX, PINP and BMD with risk genotype or no risk genotype in the control.

Genotype	Genotype		P value
	Risk	No risk
	rs7984870 CC	rs7984870 GG
	(n = 43)	(n = 59)
E2 (pg/ml)	11.16 ± 5.98	11.30 ± 6.10	0.777
CTX (pg/ml)	222.2 ± 89.2	218.9 ± 88.6	0.051
PINP (pg/ml)	334.1± 125.8	331.0 ± 121.0	0.168
Lumbar spine BMD (g/cm2)	0.975± 0.207	1.002 ± 0.225	0.772
WHO-criteria	n (%)	n (%)
Lumbar spine BMD T-score
<−2.5 SD (Osteoporosis)	5(11.6)	5(8.5)	0.597
−2.5 SD–−1.0 SD (Osteopenia)	16(37.2)	21(35.6)	0.867
−>1.0 SD (Normal)	22(51.2)	33(56.0)	0.633
	rs2073618 CC	rs2073618 GG
	(n = 24)	(n = 83)
E2 (pg/ml)	11.21 ± 5.67	11.28 ± 5.89	0.900
CTX (pg/ml)	223.9 ± 95.9	219.5 ±88.9	0.053
PINP (pg/ml)	335.2± 123.8	332.1 ± 118.5	0.230
Lumbar spine BMD (g/cm2)	0.968 ± 0.211	0.999 ± 0.245	0.775
WHO-criteria	n (%)	n (%)
Lumbar spine BMD T-score
<−2.5 SD (Osteoporosis)	3(12.5)	7(8.4)	0.545
−2.5 SD–−1.0 SD (Osteopenia)	9(37.5)	30(36.1)	0.903
−>1.0 SD (Normal)	12(50.0)	46(55.4)	0.639

Note: E2 = estradiol; BMD = bone mineral density.