Table 1.

Cis-SNPs that affect kinase activity are associated with gene expression levels in trans

SNP	Chr	Position (GRCh38)	Nearby gene	Reference allele	Associated genes	P-value
rs11865086	16	30119172	ERK	C	ANGEL1	7.6 × 10−4
rs2005219	16	30129937	ERK	A	BFAR	9.1 × 10−5
rs1292034	17	59912499	p70S6K	G	NCBP1	2.2 × 10−5
rs1292034	17	59912499	p70S6K	G	INF2	1.2 × 10−4
rs1292034	17	59912499	p70S6K	G	FADS1	3.3 × 10−4
rs1292034	17	59912499	p70S6K	G	FADS1	6.0 × 10−4
rs1292034	17	59912499	p70S6K	G	PMAIP1	8.2 × 10−4
rs180515	17	59946914	p70S6K	G	RANBP10	7.5 × 10−4
rs180519	17	59938910	p70S6K	G	NCBP1	2.2 × 10−5
rs180519	17	59938910	p70S6K	G	INF2	3.1 × 10−4
rs180519	17	59938910	p70S6K	G	FADS1	6.8 × 10−4
rs180519	17	59938910	p70S6K	G	KIAA0090	7.3 × 10−4
rs180519	17	59938910	p70S6K	G	FADS1	8.1 × 10−4
rs8071475	17	59896559	p70S6K	C	ACSL3	8.5 × 10−4
rs2293152	17	42329511	STAT3	G	CHST1	6.1 × 10−4
rs6503695	17	42347515	STAT3	C	ARL4A	2.0 × 10−5
rs6503695	17	42347515	STAT3	C	UCHL3	3.8 × 10−4
rs6503695	17	42347515	STAT3	C	JUN	7.1 × 10−4
rs6503695	17	42347515	STAT3	C	KPNA1	9.0 × 10−4
rs6503697	17	42349561	STAT3	T	ARL4A	2.0 × 10−5
rs6503697	17	42349561	STAT3	T	KPNA1	4.6 × 10−4
rs6503697	17	42349561	STAT3	T	UCHL3	6.4 × 10−4