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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Vascul Pharmacol. 2015 May 23;72:163–171. doi: 10.1016/j.vph.2015.05.007

Figure 4. Mfn-1 is expressed in HUVECs and mediates pro-angiogenic response.

Figure 4

Treatment with MnTBAP increases Mfn-1 expression in a time-dependent manner (A). MnTBAP-mediated activation of Akt and eNOS is inhibited after silencing of Mfn-1 (B). MnTBAP induced tube formation is prevented after silencing of Mfn-1 in comparison to control cells (C). Data are presented as mean±SEM and are representative for 3 independent experiments. *P≤0.05, **P≤ 0.005. Scale bar: 100µm.