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. 2015 Jun 11;34(14):1889–1904. doi: 10.15252/embj.201489923

Figure 1.

Figure 1

Relationship between Su(H) binding and the chromatin state

  • A E(spl)-C along with the histone modification data used to generate the chromatin signatures, where enrichment is shaded brown (highly enriched) to blue (depleted). Su(H) binding profile for BG3 cells (brown graph: fold enrichment, Log2 scale is −1.2 to 3.89, and blue shading indicates significant peaks 1% FDR) aligned with the chromatin map colour coded as in (B). Gene models are depicted in blue.
  • B Summary of the 11 chromatin signatures derived from Hidden Markov model, showing enrichments for a subset of histone modifications, brown (highly enriched) to blue (depleted) (see Supplementary Fig S1 for full profiles and comparisons).
  • C Numbers and extent of overlap in Su(H)-occupied regions between Kc and BG3 cells, the Su(H) motif was highly enriched in both data sets (P-values 4.2 × 10−10 and 2.12 × 10−14).
  • D, E Distribution of Su(H)-bound regions according to chromatin type in BG3 (D) and Kc (E) cells; chromatin is colour coded according to the scheme in (B) and Supplementary Fig S1A. Grey bars indicate the proportion of the genome in each chromatin signature.