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. 2015 Apr 27;64(3):305–312. doi: 10.1538/expanim.15-0001

Fig. 3.

Fig. 3.

The postnatal regulation of insulin and glucagon content, and the plasma glucose level are mediated by Mafa and Mafb. (A) Insulin contents in WT, B1, A0, and A0B1 pancreata at E18.5 and 1, 2, and 4 weeks of age. Values are presented as means ± SEM (n=3−9 per group; *P<0.05, vs. WT; **P<0.05, vs. B1). (B) Glucagon contents in WT and B1 pancreata at E18.5 and 1, 2, and 4 weeks of age. Values are presented as means ± SEM (n=5−10 per group; *P<0.05, vs. WT). (C) Fasting blood glucose levels in WT and mutants at 8 and 20 weeks of age (n=10−25 per group; *P<0.05, vs. WT; **P<0.05, vs. A0). Mice genotypes are abbreviated as follows: wild-type (WT), Mafb+/− (B1), Mafa−/− (A0), Mafa−/−; Mafb+/− (A0B1), Mafb−/− (B0), and Mafa−/−; Mafb−/− (A0B0) mice.