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Association of different genotypes and alleles of –378T/C polymorphism with severity of IVDD
| Genotype | n | Grade 2 | Grade 3 | Grade 4 | Value of p |
|---|---|---|---|---|---|
| TT | 370 | 59 (15.9%) | 93 (25.1%) | 218 (58.9%) | < 0.001 |
| CT | 387 | 78 (20.2%) | 112 (28.9%) | 197 (50.9%) | |
| CC | 151 | 76 (50.3%) | 48 (31.8%) | 27 (17.9%) | |
| T | 1127 | 196 (17.4%) | 298 (26.4%) | 633 (56.2%) | < 0.001 |
| C | 689 | 230 (33.4%) | 208 (30.2%) | 251 (36.4%) |
