Table I.

Apolipoprotein E genotype/allele frequencies in schizophrenia patients and matched controls

Genotype/allele	Schizophrenia (N = 180)		Control (N = 200)		Value of p	RR	EF*/PF
	N	Frequency (%)	N	Frequency (%)
ε3/ε3	126	70.00	183	91.50	0.0001♣	0.217	0.598
ε3/ε4	21	11.67	17	8.50	0.3100	1.449	0.171*
ε2/ε3	27	15.00	0	0	0.0001♣	–	–
ε2/ε4	6	3.33	0	0	0.0100♣	–	–
ε2/ε2	0	0	0	0	–	–	–
ε4/ε4	0	0	0	0	–	–	–
ε3	300	83.33	383	95.75	0.0001♣	0.222	0.606
ε4	27	7.50	17	4.25	0.0600	1.826	0.277*
ε2	33	9.17	0	0	0.0001♣	–	–

N – Number of subjects,

^♣statistically significant, EF – etiological fraction, PF – preventive fraction.