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. 2015 Aug 28;21(32):9526–9533. doi: 10.3748/wjg.v21.i32.9526

Table 2.

Studies of interferon-free regimens for treatment of hepatitis C virus positive liver transplant candidates

Ref. No. of patients Severity of liver disease based on CP score Antiviral scheme (duration) Virological response
Curry et al[16] 61 ≤ 7 SOF + RBV (for 48 wk or until LT) 69% (12 wk after LT)
Afdhal et al[17] 40 5-10 SOF + RBV (48 wk) 100% and 93% for Child class A and B, respectively at 24 wk under treatment
Gane et al[18] 20 7-9 SOF + Ledipasvir ± RBV(12 wk) 89%
Flamm et al[19] 108 Decompensated cirrhosis (CP score range: 7-12) Ledipasvir/SOF + RBV(12 or 24 wk) 87% and 89% (for 12 and 24 wk, respectively)

CP: Child-Pugh; SOF: Sofosbuvir; RBV: Ribavirin.