Table 2.
Virological, biochemical and serologic outcomes after long-term treatment in both entecavir and lamivudine arms n (%)
ETV | LAM ± ADV | P-value | |
n | 19 | 23 | |
HBV DNA < 1000 IU/mL | 18 (94.74) | 22 (95.65) | 0.8897 |
HBV DNA < 60 IU/mL | 10/13 (76.92) | 11/16 (68.75) | 0.6243 |
ALT ≤ 1 × upper limit of normal | 18 (94.74) | 17 (73.91) | 0.0715 |
HBeAg loss/HBeAg positive at baseline | 6/13 (46.15) | 10/14 (71.43) | 0.1817 |
HBe seroconversion/HBeAg positivity at baseline | 5/13 (38.46) | 6/14 (42.86) | 0.8163 |
HBsAg loss | 0 (0) | 0 (0) | - |
ETV: Entecavir; LAM: Lamivudine; ADV: Adefovir; HBV: Hepatitis B virus; ALT: Alanine aminotransferase; HBeAg: Hepatitis B e antigen; HBsAg: Hepatitis B surface antigen.