TABLE 4.

Effects of vitamin B-12 on serum concentrations of vitamin B-12, holotranscobalamin, homocysteine, folate, and hemoglobin¹

	Vitamin B-12				Placebo
Serum measure	n	Baseline	12 mo	Change from baseline, %	n	Baseline	12 mo	Change from baseline, %
Vitamin B-12, pmol/L	74	231.3 ± 52.02	640.9 ± 199.3	177	70	235.4 ± 60.7	235.7 ± 77.5	0
Holotranscobalamin, pmol/L	71	55.7 ± 21.5	240.0 ± 162.9	331	70	51.8 ± 17.5	54.2 ± 29.5	5
Homocysteine, μmol/L	73	17.1 ± 4.6	14.2 ± 4.2	−17	70	17.2 ± 5.6	17.4 ± 6.0	1
Folate, nmol/L	72	20.7 ± 12.3	20.2 ± 11.6	−2	71	21.0 ± 13.8	20.4 ± 14.0	−3
Hemoglobin, g/L	78	140.5 ± 11.0	140.0 ± 10.7	0	71	137.9 ± 12.8	137.2 ± 12.6	0

¹Small amounts of missing data (n < 10/analyte).

²Mean ± SD (all such values).