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. 2015 Aug 25;5:13470. doi: 10.1038/srep13470

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Copyright © 2015, Macmillan Publishers Limited

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(A–D) 786-O and OS-RC-2 cells were pretreated with HCRP-1 siRNA and the EGFR inhibitor, AG1478 (1 nmol/L), or EGFR siRNA. Cell migration and Matrigel cell invasion were evaluated after HCRP-1 siRNA treatment and treatment with AG1478 or EGFR siRNA. Representative fields of migrating or invading cells on the membrane (magnification, ×200). The data are presented as mean ± SD for triplicate determinations. *P < 0.05 versus siCtrl group; ^#P < 0.05 versus siHCRP-1 group.