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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: J Immunol. 2015 Sep 1;195(5):1933–1937. doi: 10.4049/jimmunol.1501209

Figure 2. ABCs in age, autoimmunity and infection.

Figure 2

Function and the outcome of ABCs appearance in aged animals is still unknown. In autoimmune animals, ABCs produce high titers of autoantibodies (mostly of IgG2a/c isotype) upon stimulation, which may be the cause of autoimmunity. During the infection, ABCs produce anti-viral IgG (mostly IgG2a/c), which is required for the efficient viral clearance.