Table 3.
Univariate and multivariate analyses of CSS in ESCC patients
| Univariate analysis | P-value | Multivariate analysis | P-value | |
|---|---|---|---|---|
|
|
|
|||
| HR (95% CI) | HR (95% CI) | |||
| Age (years) | 0.895 | - | - | |
| ≤60 | 1.000 | |||
| >60 | 1.019 (0.772-1.345) | |||
| Gender | 0.324 | - | - | |
| Female | 1.000 | |||
| Male | 1.244 (0.806-1.921) | |||
| Tumor length (cm) | <0.001 | 0.622 | ||
| ≤3.0 | 1.000 | 1.000 | ||
| >3.0 | 2.040 (1.441-2.887) | 1.106 (0.740-1.654) | ||
| Tumor location | 0.343 | - | - | |
| Upper/Middle | 1.000 | |||
| Lower | 1.119 (0.887-1.413) | |||
| Vessel invasion | <0.001 | 0.529 | ||
| Negative | 1.000 | 1.000 | ||
| Positive | 1.862 (1.338-2.591) | 1.121 (0.785-1.603) | ||
| Differentiation | 0.010 | 0.320 | ||
| Well/Moderate | 1.000 | 1.000 | ||
| Poor | 1.356 (1.075-1.711) | 1.139 (0.881-1.474) | ||
| T stage | <0.001 | 0.015 | ||
| T1-2 | 1.000 | 1.000 | ||
| T3-4 | 2.540 (1.831-3.524) | 1.634 (1.101-2.425) | ||
| N stage | <0.001 | <0.001 | ||
| N0 | 1.000 | 1.000 | ||
| N1-3 | 2.903 (2.183-3.862) | 1.919 (1.392-2.645) | ||
| Adjuvant therapy | 0.351 | - | - | |
| No | 1.000 | |||
| Yes | 1.150 (0.857-1.543) | |||
| GPS | <0.001 | <0.001 | ||
| 0 | 1.000 | 1.000 | ||
| 1-2 | 1.815 (1.516-2.172) | 1.438 (1.176-1.759) | ||
| NLR | <0.001 | 0.929 | ||
| 0 (≤3.45) | 1.000 | 1.000 | ||
| 1 (>3.45) | 2.116 (1.598-2.801) | 1.016 (0.723-1.426) | ||
| PLR | <0.001 | 0.002 | ||
| 0 (≤166.5) | 1.000 | 1.000 | ||
| 1 (>166.5) | 2.240 (1.696-2.960) | 1.655 (1.207-2.269) | ||
| LMR | <0.001 | 0.002 | ||
| 0 (>2.30) | 1.000 | 1.000 | ||
| 1 (≤2.30) | 2.105 (1.587-2.790) | 1.624 (1.202-2.195) |