Table 3. Reported Mutations and Associated Resistance Determined by in Vitro Assays.

Mutation	Lamivudine	Adefovir*	Entecavir	Telbivudine	Tenofovir*
I169T	>1000	1.0	>1000	>100	No data
A181T	2–6	1–5	No data	No data	1–1.5
A181V	2–6	1–5	No data	No data	2.9–10
T184G	>1000	2.0	>1000	>1000	0.6–6.9
S202I	>1000	2.0	>1000	>1000	0.6–6.9
M204I (YMDD)	>1000	0.7	30	>1000	0.7–3.4
M204V (YMDD)	>1000	0.7	No data	1.2	0.7–3.4
V214A	10–20	7–10	No data	7–10	>10
Q214S	10–20	7–10	No data	7–10	>10
N236T	3–8	7–10	0.67	2.4	2.9–10
M250V	>1000	1.0	>1000	1.0	0.6–6.9
L80I + M204I	>1000	>10	No data	>1000	>10
L180M + M204V	>1000	0.2	30	133	3.4

Source: Ref [59]