Table 1. In Vitro Activity of Caspofungin Against Fluconazole-Resistant Candida spp. Clinical Isolates in Iran a,b.
Fluconazole-Resistant Isolates MIC ≥ 64 | Caspofungin-Non Susceptible Isolates (MIC > 2) in Fluconazole-Resistant Isolates | Caspofungin-Susceptible Isolates (MIC ≤ 2) in Fluconazole-Resistant Isolates | |
---|---|---|---|
C.albicans (108) | 8 (7.4) | 1 (12.5) | 7 (87.5) |
C. glabrata (51) | 15 (29.4) | 1 (6.6) | 14 (93.4) |
C. tropical (16) | 3 (18.7) | 0 | 3 (100) |
C. krusei (7) | 5 (71.4) | 1 (20) | 4 (80) |
C. dubliniensis (4) | 0 | 0 | 0 |
Other Candia spp. (11) | 0 | 0 | 0 |
Unknown yeasts (10) | 2 (20) | 0 | 2 (100) |
Total (207) | 33 (16) | 3 (9) | 30 (91) |
a Data are presented as NO. (%).
b Other Candida spp. Includes: C. kefyer (3), C. femata (3), C. guilliermondii (2), C. parapsilosis (1), C.ciferii (1), C.incanspiqua (1).