Table 1. Genes that are involved in cell or organ morphogenesis and differentially expressed in hPSCs with ST6GAL1 knockdown.
| Gene Name | Fold Change (knockdown/control) | P value (F-test) |
|---|---|---|
| ANTXR1 | 1.358615 | 0.004427 |
| COL3A1 | 18.10201 | 3.27E-07 |
| COL6A2 | 1.877785 | 0.002152 |
| COL6A3 | 4.273398 | 0.00015 |
| DAB2 | 4.075949 | 0.000344 |
| DKK1 | 1.911963 | 0.004 |
| FN1 | 2.018123 | 0.001211 |
| MEG3 | 2.525871 | 0.000155 |
| NTF3 | 1.498846 | 0.003855 |
| PRSS23 | 3.534211 | 0.001322 |
| RPS6KA2 | 1.768516 | 0.00018 |
| S100A4 | 6.758956 | 1.93E-05 |
| S100A6 | 3.890132 | 0.000399 |
| SLIT3 | 2.238777 | 0.001546 |
| SNAI2 | 4.19717 | 6.73E-05 |
| TRAK1 | 1.606 | 0.001001 |
| TSPO | 1.745324 | 0.004938 |
| ANGPT1 | 1.608027 | 0.000904 |
| ARID5B | 3.490712 | 0.000275 |
| CD44 | 3.305001 | 0.004976 |
| COL1A2 | 5.251568 | 3.90E-06 |
| COL5A1 | 5.055658 | 0.000118 |
| COL8A1 | 6.030956 | 0.001054 |
| COMP | 2.422019 | 0.000522 |
| CRYGB | 1.326064 | 8.74E-05 |
| DCN | 58.4075 | 6.95E-10 |
| ENG | 1.674513 | 0.001303 |
| FZD1 | 1.20207 | 0.001537 |
| GAS1 | 5.137223 | 0.000236 |
| GREM1 | 9.592929 | 9.73E-05 |
| HEG1 | 2.404444 | 0.000406 |
| HOXA5 | 1.164782 | 0.003494 |
| HOXC4 | 1.773052 | 0.001589 |
| HOXC8 | 4.19109 | 0.000182 |
| ID2 | 2.850354 | 0.003447 |
| IGFBP5 | 2.114798 | 5.94E-05 |
| MEF2D | 0.813538 | 0.003326 |
| MSX1 | 3.0921 | 0.004755 |
| MYLK | 1.946184 | 0.004114 |
| NNMT | 7.347762 | 4.22E-05 |
| NRP1 | 2.751723 | 0.000539 |
| OSR1 | 2.245728 | 0.001449 |
| PDGFRA | 2.562541 | 0.000506 |
| PHACTR3 | 2.016834 | 0.002722 |
| PITX2 | 1.47441 | 0.000332 |
| PTPRM | 1.444159 | 0.004339 |
| RDH10 | 1.565426 | 0.002461 |
| RTN4 | 0.857992 | 0.00114 |
| TGFBR2 | 1.583883 | 0.002067 |
| TSHZ1 | 1.545548 | 0.003036 |
| TWIST2 | 2.225789 | 0.001767 |
| TXNDC5 | 1.195257 | 0.003299 |
| VEGFC | 1.696232 | 0.001064 |