Table 1.

Brighton and Villefranche diagnostic criteria

Hypermobility syndrome	Ehlers–Danlos (hypermobility type)
Brighton criteria	Villefranche criteria
Major criteria
Generalized joint hypermobility (Beighton score ≥4: currently or historically)	Generalized joint hypermobility (Beighton score ≥5)
Arthralgia (≥4 joints, ≥3 months)	Skin involvement (hyperextensibility; smooth, soft, and velvety skin)
Minor criteria
Beighton scores of 1, 2, and 3 (0, 1, 2, or 3 if aged ≥50 years)	Recurring joint dislocations
Arthralgia in 1, 2, or 3 joints or back pain, spondylosis, spondylolysis, or spondylolisthesis	Chronic joint and limb pain (≥3 months)
Dislocation/subluxation in more than one joint, or in one joint on more than one occasion	Positive family history
Soft tissue rheumatism: >3 lesions (eg, epicondylitis, tenosynovitis, bursitis)
Marfanoid habitus: tall, slim, span/height ratio >1.03, upper: lower segment ratio <0.89, arachnodactyly
Abnormal skin: striae, hyperextensibility, thin skin, papyraceous scarring
Eye signs: drooping eyelids or myopia or antimongoloid slant
Varicose veins, hernia, or uterine/rectal prolapsed