Table 3.
Non-Stress-Dependent Results3
Behavior | Direction | Knockout Genotype |
Publication |
---|---|---|---|
MSUS maternal care | Increased | All FB1a | O’Leary et al., 2014 |
Light/dark Box | Reduced anxiety* | FB1b | Jacobson et al., 2007b |
Elevated zero maze | Increased anxiety | FB1a, FB1b | Jacobson et al, 2007b |
MSUS tail suspension test | Increased immobility | All FB1a, All MB1a | O’Leary et al., 2014 |
decreased immobility | All MB1b |
All “directions” are compared to wild type mice in the same task unless marked by an asterisk (*), thereby indicating the direction is compared to the other isoform knockout.
“MSUS” in the behavior column indicates that the task took place following unpredictable maternal stress. In the genotype column, “FBla” and “FB1b” indicate female mice. “MB1a” and “MB1b” indicate male mice. “NMS” indicates no stress, and “MS” indicates maternal stress. “All” indicates a main effect of genotype – results were not specific to stress condition. O’Leary et al. 2014 tested MSUS saccharin preference only in female mice, and MSUS female urine sniffing only in male mice.