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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Neurosci Biobehav Rev. 2015 Aug 15;57:70–87. doi: 10.1016/j.neubiorev.2015.08.007

Table 3.

Non-Stress-Dependent Results3

Behavior Direction Knockout
Genotype
Publication
MSUS maternal care Increased All FB1a O’Leary et al., 2014
Light/dark Box Reduced anxiety* FB1b Jacobson et al., 2007b
Elevated zero maze Increased anxiety FB1a, FB1b Jacobson et al, 2007b
MSUS tail suspension test Increased immobility All FB1a, All MB1a O’Leary et al., 2014
decreased immobility All MB1b
3

All “directions” are compared to wild type mice in the same task unless marked by an asterisk (*), thereby indicating the direction is compared to the other isoform knockout.

“MSUS” in the behavior column indicates that the task took place following unpredictable maternal stress. In the genotype column, “FBla” and “FB1b” indicate female mice. “MB1a” and “MB1b” indicate male mice. “NMS” indicates no stress, and “MS” indicates maternal stress. “All” indicates a main effect of genotype – results were not specific to stress condition. O’Leary et al. 2014 tested MSUS saccharin preference only in female mice, and MSUS female urine sniffing only in male mice.