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. 2015 Aug 25;15:293. doi: 10.1186/s12906-015-0816-z

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© Nguelefack et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Effects of oral administration of the methanol/methylene chloride extract of the stem bark of Croton macrostachyus (MECM) on the mechanical hyperalgesia induced by von Frey hair (0.4 g) in CFA (20 μl/paw) inflamed mice paw. In persistent treatment, response to pain was evaluated before the treatment of the day, when given. B = basal response to mechanical stimulation. N = 5; ^a p < 0.05; ^b p < 0.01; ^c p < 0.001 significantly different compared to vehicle (ANOVA two way and Bonferoni as post hoc test)