. 2015 Jun 22;19(1):270. doi: 10.1186/s13054-015-0959-9

Table 1.

Baseline characteristics

	Control period 1999, 2000, 2001 (n = 2,538)	Implementation period 2002, 2003, 2004, 2005, 2006 (n = 4,925)	Tight glucose control period 2007, 2008, 2009 (n = 2,730)	P value
Male gender, %	60.3	63.1	60.7	0.782^a
Age, years, mean (95 % CI)	57.6 (57.0, 58.3)	59.9 (59.4, 60.3)	59.6 (59.0, 60.2)	<0.002^b
Length of stay in ICU, days, median (IQR)	4.5 (2.0, 11.3)	2.8 (1.1, 8.2)	3.1 (1.8, 8.3)	<0.002^c
Length of stay hospital, days, median (IQR)	18.0 (9.0, 38.7)	14.0 (7.9, 30.5)	16.0 (8.1, 32.8)	<0.002^c
Hospitalization due to emergency, %	54.0	41.8	45.1	<0.002^a
Died on ICU, number (%)	472 (18.6)	659 (13.4)	393 (14.4)	<0.002^a
Died in hospital, number (%)	135 (5.3)	275 (5.6)	147 (5.4)	0.741^a
Number of glucose measurements per patient, median (IQR)	8 (5–18)	12 (6–37)	27 (13–76)	<0.002^c
Number of glucose measurements per patient per ICU day, median (IQR)	1.9 (1.2, 3.3)	4.8 (2.8, 7.8)	8.9 (7.3, 10.6)	<0.002^c
Number of potassium measurements per patient, median (IQR)	10 (6–21)	9 (6–17)	9 (6–20)	<0.002^c
Number of potassium measurements per patient per ICU day, median (IQR)	2.3 (1.5, 3.5)	2.8 (1.9, 4.8)	2.8 (2.0, 3.9)	<0.002^c
pH, mean (95 % CI)	7.42 (7.38, 7.45)^†	7.39 (7.39, 7.39)^{†††††}	7.39 (7.39, 7.39)^††	0.125^b
Creatinine, mean (95 % CI)	120.6 (115.7, 125.4)^†††	108.5 (105.6, 111.4) ^{††††††}	111.5 (107.5, 115.5)^††††	<0.002^b

P values represent differences between control period and tight glucose control period. ^aChi square test; ^bindependent samples t test; ^cMann-Whitney U test; ^†0.6 % missing; ^††8.6 % missing; ^†††0.1 % missing; ^††††0.7 % missing; ^{†††††}0.6 % missing; ^{††††††}0.5 % missing