Table 3.
Differences in Within-Person Daily Knee Pain Variability by COMT rs4680, and OPRM1 rs1799971
| Daily Knee Pain | COMT | P-value | OPRM1 | P-value |
|---|---|---|---|---|
| Estimate (SE) | Estimate (SE) | |||
| Beginning of Day | −0.11 (0.07) | .160 | 0.21 (0.08) | .009 |
| Afternoon | −0.24 (0.07) | .001 | 0.13 (0.08) | .084 |
| End of Day | −0.28 (0.07) | .0002 | 0.18 (0.08) | .028 |
| Across the Day | −0.15 (0.07) | .030 | 0.15 (0.07) | .037 |
Notes. Across the Day = average of beginning of day, afternoon, and end of day. All analyses control for age, race, sex, and day in study (i.e., 1 to 22). Coding of COMT rs4680: G-G = 0; A-A, A-G = 1. Coding of OPRM1 rs1799971: A-G = 0, A-A = 1.