| 3 |
Retinol metabolism |
2.09E-02 |
BCMO1,UGT1A5 |
|
Folate biosynthesis |
4.11E-02 |
ALPL |
|
Other types of O-glycan biosynthesis |
1.02E-02 |
B4GALT1, UGT1A5 |
|
Glycosaminoglycan biosynthesis—keratan sulfate |
2.39E-03 |
B3GNT7, B4GALT1 |
| 4 |
Biosynthesis of unsaturated fatty acids |
3.18E-02 |
ACOT7, ACOT1, ACOT3 |
|
Metabolic pathways |
4.55E-02 |
CYP3A25,ALOX5,ACSS1,CYP3A1,PRODH,LPIN1,GAL3ST1,TPI1, CKM,CBR1,PKM,CYP17A1,NME2,POLR2H,PGAM2,AK5,CKMT2,GFPT2,CKM,DHODH,PCYT1B,LAO1, PCK1,LDHA,NDUFV1,PTGDS, PISD,ALDOA,IMPA1,GLS,GADL1, PIGV,XYLT1,IDH2,GADL1,AMPD, HK1, PHOSPHO1 |
|
Thyroid hormone synthesis |
1.40E-05 |
HSPA5,HSPA5,HSPA5,PDIA4, HSPA5,HSPA5,HSPA5,HSP90B1, ATP1A3,HSPA5,HSPA5 |
|
Ovarian steroidogenesis |
3.96E-02 |
ACOT3,ALOX5, CYP17A1, ACOT1, IGF1R |
|
Protein processing in endoplasmic reticulum |
4.99E-07 |
HSPA5, PDIA4, CALR, HSPA5, HSPA5, HSPA5, HSP90B1, HSPA5, PDIA6, HSPA5, HYOU1, DNAJB11, HSPA5, SEC31A, DERL1, CALR, HSPA5, CALR, SSR1 |
|
Arginine and proline metabolism |
1.64E-02 |
CKM, GLS, PRODH, CKM, CKMT2 |
|
Protein export |
2.30E-07 |
HSPA5, HSPA5, HSPA5, HSPA5, HSPA5, HSPA5, HSPA5, HSPA5 |
|
Biosynthesis of amino acids |
3.23E-02 |
PGAM2, ALDOA, IDH2, TPI1, PKM |
|
Glycolysis/gluconeogenesis |
1.89E-04 |
PKM, PGAM2, PCK1, LDHA, ALDOA, HK1, ACSS1, TPI1 |
|
Carbon metabolism |
1.57E-02 |
TPI1, PKM, PGAM2, ALDOA, IDH2, HK1, ACSS1 |
|
Proximal tubule bicarbonate reclamation |
1.59E-02 |
SLC9A3, PCK1, GLS, ATP1A3 |
|
Pyruvate metabolism |
2.10E-02 |
ACSS1, PKM, PCK1, LDHA |
|
Chemical carcinogenesis |
3.96E-02 |
GSTM5, CYP3A25, CYP3A13, CBR1, GSTO1 |
|
Metabolism of xenobiotics by cytochrome P450 |
3.83E-02 |
GSTO1, GSTM5, CYP3A25, CYP3A13, CBR1 |
|
p53 signaling pathway |
3.12E-02 |
GADD45G,VAT1L,IGFBP3,GADD45B,ZMAT3 |
|
PI3K-Akt signaling pathway |
3.39E-02 |
DDIT4,VAT1L, IGFBP3, GADD45B, ZMAT3 |
|
Cardiac muscle contraction |
3.00E-03 |
MYH6,RYR1,MYH7,ATP2A1,MYH6, TPM1, TNNC2, ACTC1, ATP1A3 |
|
Dilated cardiomyopathy |
5.50E-04 |
ACTC1, MYH6, RYR1, MYH7, TTN, TITIN, ATP2A1, MYH6, TPM1, TNNC2, ACTB, SGCG |
|
Hypertrophic cardiomyopathy (HCM) |
2.97E-04 |
ACTB, SGCG, ACTC1, MYH6, RYR1, MYH7, TTN, TITIN, ATP2A1, MYH6, TPM1, TNNC2 |
|
Prion disease |
8.71E-07 |
HSPA5,HSPA5,HSPA5,HSPA5,C7,HSPA5,EGR1,HSPA5,HSPA5,HSPA5 |
|
Viral myocarditis |
9.13E-07 |
MYH4,MYH4,ACTB,SGCG,MYH6,MYH4, MYH13, MYH7, MYH2, MYH1, EIF4G3, MYH2, MYH4, MYH6, MYH4, MYH4, MYH4 |
|
Antigen processing and presentation |
2.65E-05 |
CALR, HSPA5, HSPA5, HSPA5, HSPA5, HSPA5, HSPA5, CALR, HSPA5, CALR, HSPA5 |
|
Chagas disease |
3.32E-02 |
CALR, GNA14, CALR, IRAK1, JUN, CALR, TLR13 |
|
Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
4.57E-02 |
ACTB,SGCG,RYR1,ACTN3,ATP2A1,DSG2 |
|
HIF-1 signaling pathway |
2.08E-02 |
EGLN3, IGF1R, LDHA, CAMK2D, EPO, ALDOA, HK1 |
|
Tight junction |
1.37E-06 |
MYH6, CLDN4, MYH4, MYH13, MYH7, ACTN3, MYH2, MYH1, MYH2, MYLPF, MYH4, MYH6, MYH4, MYH4, MYH4, MYH4, MYH4, ACTB, CLDN4, MYLPF |
