Table 1.

Genetic divergence within WHO/OIE/FAO H5 clades since January 1, 2013

Previous clades	Intra-clade (%)	Nearest clade	Inter-clade (%)	Updated clades	Intra-clade	Nearest clade	Inter-clade
0	2.05	3	2.29	2007 (last reported in)
1	1.01	8	2.00	2010
1.1	0.93	1.1.1	2.25	2008
1.1.1	1.47	1.1	2.25	2012
1.1.2	1.66	1.1.1	3.13	Limited detection in Mekong River Delta in 2014
3	1.16	8	1.82	2001
4	1.78	3	2.69	2006
5	1.76	8	2.60	2009
6	1.33	8	2.07	2004
7	3.01	3	3.29	2008
7.1	1.26	7.2	5.08	2008
7.2	2.78	7.1	5.08	Limited detection in 2013 and 2014
8	0.69	9	1.46	2002
9	1.55	8	1.46	2009
2.1.1	1.48	2.1.2	2.08	2007
2.1.2	1.09	2.1.1	2.08	2006
2.1.3	1.14	2.1.1	2.83	2007
2.1.3.1	1.90	2.1.3.3	2.61	2011
2.1.3.2	1.74	2.1.3.1	2.79	2010
2.1.3.2a (Indonesia)	2.03	2.1.3.2	3.52	2.1.3.2a	1.38%	2.1.3.2b	2.72%
				2.1.3.2b	1.43%	2.1.3.2a	2.72%
2.1.3.3	1.60	2.1.3.1	2.61	2010
2.2	1.21	2.2.2	2.18	2008
2.2.1 (Egypt)	1.70	2.2	2.25	2.2.1	1.44%	2.2	1.93%
				2.2.1.2	1.05%	2.2.1	2.14%
2.2.1.1	1.53	2.2.1.1a	2.38	2010
2.2.1.1a	1.29	2.2.1.1	2.38	2011
2.2.2	1.01	2.2.2.1	2.14	2010
2.2.2.1	1.45	2.2.2	2.14	2011
2.3.1	1.07	2.3.2	2.29	2005
2.3.2	1.20	2.3.1	2.29	2006
2.3.2.1	1.55	2.3.2.1a	3.17	2011
2.3.2.1a	1.93	2.3.2.1c	3.12	Limited detection in Bangladesh during 2014
2.3.2.1b	1.67	2.3.2.1	3.43	Limited detection in China and Hong Kong SAR in 2013
2.3.2.1c	1.75	2.3.2.1a	3.12	Cambodia, China, Laos, Indonesia, Vietnam in 2014
2.3.3	0.76	2.3.1	2.79	2006
2.3.4 (widespread)	2.95	2.3.4.3	2.77	2.3.4	1.59%	2.3.4.3	2.05%
				2.3.4.4	2.63%	2.3.4	6.65%
2.3.4.1	1.09	2.3.4.3	3.80	2010
2.3.4.2	1.66	2.3.4.3	2.78	Outliers detected in China in 2013*
2.3.4.3	0.78	2.3.4	2.75	2009
2.4	1.03	2.1.1	2.19	2005
2.5	1.09	2.2	2.61	2006

^*Outliers represented by A/Guizhou/1/2013 and A/Guizhou/2/2013; viruses in this cluster were not reported in 2014.