Table 5.
Effect of encapsulated IgY on performance and the incidence of diarrhea in pigs challenged with K88+ ETEC1
| Items | No. of pigs | Percentage of pigs with diarrhea after specific times (Fecal score in brackets2) | Weight gain, g3 | Recovery rate, (%) | |||
|---|---|---|---|---|---|---|---|
| 9 h | 24 h | 48 h | 72 h | ||||
| Negative control, unchallenged | 4 | 0 % (0.5) | 0 % (0) | 0 % (0.4) | 0 % (0) | +1400 ± 129a | —— |
| Positive control | 4 | 75 % (2.5) | 75 % (2.5) | 75 % (2.0) | 75 % (2.0) | −162.5 ± 25d | 0 % |
| Non-encapsulated IgY | 4 | 100 % (2.0) | 75 % (1.3) | 25 % (1.0) | 0 % (0) | +937.5 ± 111b | 100 % |
| Microencapsulated IgY | 4 | 75 % (2.0) | 0 % (0) | 0 % (0) | 0 % (0) | +1325 ± 119a | 100 % |
| Aureomycin | 4 | 100 % (2.0) | 50 % (2.0) | 75 % (1.5) | 50 % (1.5) | +650 ± 71c | 50 % |
Li et al. [83]
1All pigs except negative control were orally challenged with 5 mL of viable E. coli K88 organisms (1011 cfu/mL per pig) at time 0 h. Challenged pigs were left untreated (positive control) or treated three times (−1, 4 and 9 h after bacterial challenge) on the first day and twice a day for two consecutive days each time with 0.4 g non-encapsulated IgY, 2 g of microencapsulated IgY (equivalent to 0.4 g of IgY) or 0.25 g of aureomycin. Diarrhea and weight gain were assessed for 3 days after challenge
2FC score is the mean fecal consistency score: 0, normal; 1, soft feces; 2, mild diarrhea; 3, severe diarrhea. Pigs with a fecal score of < 1 were considered not to have diarrhea
3Means in a column followed by same or no letter do not differ (P > 0.05)