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. 2015 Mar 8;19(8):1916–1928. doi: 10.1111/jcmm.12566

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© 2015 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Cytotoxicity of PAC-1 and WF-208 against cancerous cells and normal cells. (A) The IC₅₀ of PAC-1 and WF-208 in various cancerous cells. (B) The IC₅₀ of PAC-1 and WF-208 in various normal cells. (C) The cytotoxicity of WF-208 and PAC-1 against mouse primary cortical neuron cells. (D) The mean of IC₅₀ in cancerous cells and normal cells and selection index (SI) of WF-208.