Table 2.
Basic characteristics of experimental groups at the termination of study
| Wistar | SHR | SHRL-withdrawn | SHR-L | |
|---|---|---|---|---|
| BW (g) | 218 ± 9 | 206 ± 4 | 199 ± 7 | 196 ± 6 |
| LVW (g) | 0.50 ± 0.03 | 0.63 ± 0.02* | 0.60 ± 0.04* | 0.43 ± 0.02# |
| LVW/BW (mg/g) | 2.3 ± 0.1 | 3.1 ± 0.1* | 2.9 ± 0.1* | 2.2 ± 0.1# |
| Kidney | 0.81 ± 0.04 | 0.73 ± 0.03 | 0.74 ± 0.04 | 0.66 ± 0.02 |
| Kidney/BW (mg/g) | 3.7 ± 0.2 | 3.5 ± 0.1 | 3.6 ± 0.1 | 3.4 ± 0.1 |
| sBP (mmHg) | 109 ± 2 | 149 ± 2* | 145 ± 2* | 105 ± 3# |
| QTc (msec.) | 81 ± 2 | 80 ± 2 | 82 ± 2 | 79 ± 3 |
Mean ± SEM (n = 8–10 per group
*
P < 0.05 versus CON
#
P < 0.05 versus SHR).
BW: bodyweight; LVW: left ventricular weight; sBP: systolic blood pressure at the 9th week of age; QTc: corrected QT interval.