Table 3.
Day | G6PD deficient | G6PD normal | P | G6PD deficient | G6PD normal | P | G6PD deficient | G6PD normal | P |
---|---|---|---|---|---|---|---|---|---|
Haemoglobin concentration (g/dL) | Changes in haemoglobin concentrations versus day 0 | Fractional changes in haemoglobin concentrations versus day 0 | |||||||
0 | 13.0 (9.6 to 16) | 13.5 (9 to 16.3) | 0.46 | – | – | – | – | ||
1 | 11.2 (8.2 to 14.9) | 12.4 (8.7 to 15.3) | 0.041 | – 1.5 (–4.0 to 1.1) | – 0.8 (– 3.2 to 3.3) | 0.059 | –12.5 (– 27.1 to 8.7) | – 6.5 (– 22.7 to 28.7) | 0.028 |
2 | 10.8 (8.2 to 15.3) | 12.4 (8.8 to 15.2) | 0.006 | – 1.7 (–5.0 to 0.6) | – 1 (– 3.5 to 2.1) | 0.047 | –13.3 (– 31.2 to 4.1) | – 7.4 (– 23.6 to 25.2) | 0.029 |
3 | 10.9 (7.5 to 14.8) | 12.8 (8.3 to 15.6) | 0.0002 | – 1.9 (–5.8 to 0.4) | – 0.8 (– 2.6 to 2.9) | 0.0003 | –15.3 (– 39.2 to 3.6) | – 6.1 (– 19.1 to 22.8) | 0.0001 |
7 | 10.9 (8.9 to 13) | 13 (9.5 to 15.7) | 0.0001 | – 2.2 (–4.9 to 0.8) | –0.5 (– 2.2 to 2.8) | 0.0002 | – 16.3 (– 33.1 to 6.5) | – 3.7 (– 17.5 to 23.3) | 0.0002 |
14 | 11.4 (9.7 to 14.1) | 12.8 (9.5 to 15.5) | 0.0067 | – 1.7 (–3.0 to 0.3) | –0.5 (– 4.2 to 2.1) | 0.005 | – 12.9 (– 22.7 to 2.7) | – 4 (– 25.7 to 18.1) | 0.0035 |
21 | 12 (11 to 15.6) | 13.3 (8.7 to 16.4) | 0.039 | – 0.6 (–2 to 1.6) | 0.3 (– 3.5 to 2.1) | 0.1 | – 4.7 (– 15.1 to 14.6) | 2.1 (– 24.3 to 16.8) | 0.11 |
28 | 12.8 (10.9 to 15.4) | 13.5 (9.5 to 16.1) | 0.26 | 0.2 (–2 to 2.6) | 0.3 (–2.3 to 2.7) | 0.62 | 1.5 (– 13.6 to 27.1) | 2.3 (– 15.8 to 21.2) | 0.58 |
All data are shown as median (range)
G6PD glucose-6-phosphate dehydrogenase