. 2015 Aug 25;13:203. doi: 10.1186/s12916-015-0441-1

Table 4.

Changes in laboratory parameters over time

Parameter	G6PDd	G6PDn	P	G6PDd	G6PDn	P	G6PDd	G6PDn	P	G6PDd	G6PDn	P
	D0			D7			D28			D56
Reticulocyte count (%)	1.7	1.3	0.051	3	1.9	0.0009	1.4	1.5	0.056	1	1.2	0.98
Reticulocyte count (%)	(0.6–3.8)	(0.5–4.5)	0.051	(1.6–3)	(0.6–7)	0.0009	(0.9–4.8)	(0.3–6)	0.056	(0.5–2.4)	(0.4–2.6)	0.98
Plasma haemoglobin (g/dL)	0.1	0.085	0.3	0.05	0.05	0.81	0.03	0.04	0.75	0.08	0.08	0.9
Plasma haemoglobin (g/dL)	(0.01–13.5)	(0.01–0.71)	0.3	(0.02–0.46)	(0–0.27)	0.81	(0.01–0.13)	(0–0.28)	0.75	(0.04–0.09)	(0–0.24)	0.9
Haptoglobin (g/L)	0.34	0.59	0.21	0.35	0.72	0.006	0.69	0.98	0.03	0.54	0.87	0.029
Haptoglobin (g/L)	(0–1.48)	(0–2.16)	0.21	(0.09–1.07)	(0.1–1.83)	0.006	(0.16–1.19)	(0.04–2.32)	0.03	(0.08–1.25)	(0.06–2.22)	0.029
Low haptoglobin^a	8/16	14/56	0.056	5/14	8/57	0.11	2/14	3/52	0.28	5/14	4/49	0.02
Low haptoglobin^a	(50)	(25)	0.056	(35.7)	(14.1)	0.11	(14.3)	(5.8)	0.28	(35.7)	(8.2)	0.02
LDH (IU/L)	308	231	0.01	350	196	0.0002	319.5	183.5	0.005	296.5	181	0.008
LDH (IU/L)	(127–800)	(23–611)	0.01	(178–700)	(58–783)	0.0002	(121–619)	(37–593)	0.005	(154–746)	(118–522)	0.008
High LDH^a	13/17	18/56	0.002	12/15	12/57	0.000	10/14	7/52	0.001	8/14	7/49	0.002
High LDH^a	(76.5)	(32.1)	0.002	(80)	(21.1)	0.000	(71.4)	(13.5)	0.001	(57.1)	(14.3)	0.002
Unconjugated bilirubin (mg/L)	2.5	3.75	0.63	1.7	1.7	0.9	1.4	1.4	0.66	1.45	1.5	0.59
Unconjugated bilirubin (mg/L)	(0.6–9.8)	(0.5–14.3)	0.63	(0.4–4.8)	(0.19–3.1)	0.9	(0.7–3.6)	(0.2–4.3)	0.66	(0.6–3.4)	(0.5–4.3)	0.59
Creatinine (μmol/L)	58	74	0.003	58	63	0.13	54.5	60.5	0.29	54.5	58	0.32
Creatinine (μmol/L)	(28–86)	(35–90)	0.003	(28–83)	(28–85)	0.13	(19–82)	(27–99)	0.29	(24–80)	(26–84)	0.32

^anumerator/denominator (%)

Low below the lower limit of normal for haptoglobin LLN (0.3 g/L), High above the upper limit of normal for LDH (255 IU/L)

G6PDd glucose-6-phosphate dehydrogenase deficient, G6PDn glucose-6-phosphate dehydrogenase normal, LDH lactate dehydrogenase