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. 2015 Aug 25;11(8):e1005433. doi: 10.1371/journal.pgen.1005433

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© 2015 Takasuga et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 3 — Affected calf (A) and cow (B) are presented. Red circles show the symptoms of thin neck, extended shoulder, thick joints of the limbs, and hip bone-enlargement. (C) Tibias from cows with FGD3 Cys-171 homozygous (NLBC-1 and K) and a non-carrier control (T) cows. They were 7.1–8.3 years old. Withers height (WH), shank circumference (SC), tibia length (TL), and circumference of tibia shaft (CT) are as follows: NLBC-1, 135.6 cm (WH), 20.4 cm (SC), 38.8 cm (TL), 13.6 cm (CT); K, 140 cm (WH), 18.5 cm (SC), 38.4 cm (TL), 13.0 cm (CT); T, 128.8 cm (WH), 17.8 cm (SC), 36.6 cm (TL), 12.0 cm (CT). The arrows indicate medial malleolus and intercondylar eminence. Dashed lines were drawn to facilitate observation.