Table 6.

Multivariable-Adjusted Competing Risks of Cause-Specific Mortality According to Baseline PCR

Type of Death	Q1: 1.85-44.58 g/g (n = 1,009)	Q2: 0.39-1.85 g/g (n = 1,009)	Q3: 0.13-0.39g/g (n = 1,009)	P
Overall	2.89 (2.32-3.60)	1.70 (1.37-2.10)	1.52 (1.22-1.88)	<0.001
CV death	2.42 (1.80-3.27)	1.64 (1.23-2.19)	1.38 (1.03-1.85)	<0.001
Fatal MI	1.98 (0.89-4.42)	1.84 (0.82-4.10)	1.92 (0.88-4.21)	0.1
Fatal stroke	3.94 (1.46-10.6)	2.10 (0.74-6.00)	1.33 (0.47-3.82)	0.004
Presumed CV death	1.81 (0.87-3.78)	1.33 (0.63-2.82)	0.75 (0.33-1.69)	0.07
Pump failure	1.59 (0.77-3.27)	1.04 (0.52-2.07)	1.36 (0.75-2.07)	0.4
CV other	3.10 (0.93-10.5)	1.09 (0.30-3.93)	1.17 (0.34-4.01)	0.1
Presumed sudden death	1.57 (0.56-4.38)	1.48 (0.57-3.83)	0.71 (0.22-2.29)	0.2
Definite sudden death	2.99 (1.68-5.30)	2.20 (1.29-3.75)	1.80 (1.05-3.08)	<0.001
Definite or presumed sudden death	2.64 (1.59-4.36)	2.03 (1.27-3.23)	1.53 (0.94-2.47)	<0.001
Non-CV death	2.63 (1.86-3.74)	1.54 (1.07-2.19)	1.50 (1.06-2.10)	<0.001
Infection	4.05 (2.13-7.73)	1.61 (0.80-3.25)	1.79 (0.93-3.46)	<0.001
Malignancy	1.67 (0.76-3.67)	1.24 (0.57-2.72)	1.75 (0.90-3.40)	0.3
Other	1.62 (0.89-2.96)	1.56 (0.90-2.71)	1.46 (0.85-2.53)	0.09
Renal	4.24 (1.59-11.3)	1.82 (0.60-5.54)	0.46 (0.11-1.87)	0.002
Unknown	4.64 (2.09-10.31	2.08 (0.88-4.90)	2.09 (0.93-4.69)	<0.001

Note: Values are given as hazard ratio (95% confidence interval). Q4 (0.003-0.13 g/g) is reference group (n = 1,009). Multivariable competing-risks models for specific causes of death. All models adjusted for for treatment, age, race, sex, diabetes, duration of diabetes, systolic and diastolic blood pressure, and history of CV disease.

Abbreviations: CV, cardiovascular; MI, myocardial infarction; PCR, protein-creatinine ratio; Q, quartile.