Table 2.
| Normal | SHAM | CKD | CKD + Omni | CKD +Omni + DFP | |
|---|---|---|---|---|---|
| (n = 4) | (n = 5) | (n = 4) | (n = 8) | (n = 9) | |
| Body weight (g) | 28±0.3 | 27.8±0.9 | 24.4±-0.8 | 22.7±1.3* | 24.5±1.4 |
| Hb (g/dl) | 15±0.8 | 12.3±2.3 | 10.9±1.3 | 12.0±0.8 | 11.5±0.83 |
| HCT (%) | 55±3 | 48±8 | 44±6 | 48±4 | 46±4 |
| WBC (k/μl) | 9.2±3 | 7.9±2.2 | 9.0±6.4 | 13.9±6.0 | 9.1±4.4 |
| Platelets (k/μl) | 560±78 | 405±251 | 206±127 | 334±208 | 186±87 |
| BUN (mg/dl) one week after nephrectomy at sacrifice | (16±9) 17±2 | (16±2)17±1 | (78±12)***55±6** | (77±8)***55±7** | (78±9)***46±5** |
| Creatinine (mg/dl) one week after nephrectomy at sacrifice | (0.13±0.09)0.2±0.02 | (0.19±0.2)0.2±0.03 | (0.49±0.1)**0.4±-0.04* | (0.48±0.1)**0.35±0.2* | (0.48±0.1)**0.3±0.08* |
| Ferritin (ng/ml) | 17±1.8 | 35±9.5 | 26±6.6 | 31±11.0 | 19±6.0† |
*p<0.05
**p<0.001, and
*** p<0.0001 as compared to sham mice.
† p<0.05 as compared to CKD plus Omniscan.