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. 2015 Aug 25;10(8):e0136302. doi: 10.1371/journal.pone.0136302

Fig 2. Serum samples from an ETEC-endemic area contain antibodies to both A- and B-subunits of LT.

Fig 2

Human patient serum from Sierra Leone were evaluated for antibodies to LT, A-subunit, and B-subunit compared to commercially purchased control serum using endpoint titer analysis. (A) Anti-LT, anti-A, and anti-B ELISA antibody titers for all tested patient samples with geometric means indicated (lines). (B) Correlations between anti-LT and anti-A (open squares) or anti-B titers (gray diamonds) by Spearman’s Rank Order Correlation Coefficient (r) analysis. Antibody responses to LT holotoxin significantly correlated with both anti-A (P<0.0001) and anti-B (P<0.0001).