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. 2015 Aug 25;10(8):e0134193. doi: 10.1371/journal.pone.0134193

Fig 4. Plots of coagulation biomarker levels or TCD velocity against total number of PRBC transfusions received over the course of the trial.

Fig 4

von Willibrand Factor (vWF) (A), thrombin antithrombin (TAT) complex (B), D-dimer (C) levels and TCD velocity (D) All 3 biomarkers and TCD velocity show significant negative correlation with number of blood PRBC transfusion. Note in the figure the almost clear separation of subjects randomized to no transfusion (open diamond) and transfusion (solid circles) arms based on the number of PRBC transfusions received. Standard care arm = Open diamond. Transfusion arm = Solid circle.