Table 2.
Longitudinal clinical and sensorimotor data
| Controls | Patients | |||
|---|---|---|---|---|
| Baseline | Month 3 | Month 9 | ||
| NIHSS (points)a | ||||
| Upper limb motor function | n.a. | 4 (1–4) | 3 (0–4) | 2 (0–2) |
| Upper limb sensory function | n.a. | 3 (0–3) | 2 (0–2) | 1 (0–1) |
| Cognitive function | n.a. | 2 (0–3) | 1 (0–2) | 0 (0–1) |
| Sum | n.a. | 4 (1–14) | 2 (0–12) | 1 (0–7) |
| Modified Rankin Scale (points)a | ||||
| Sum | n.a. | 2 (1–4) | 1 (0–3) | 1 (0–3) |
| Modified Jebsen–Taylor test (s)b | ||||
| Picking small objects | 5.7 (4.6–7.5) | 17.0 (5.3–76.1) | 10.7 (4.0–45.5) | 8.5 (4.7–24.1) |
| 6.1 (4.7–8.3) | 7.5 (3.9–15.1) | 6.2 (3.9–10.4) | 6.0 (1.4–9.8) | |
| Stacking checkers | 4.5 (3.4–7.5) | 15.8 (6.0–63.1) | 8.3 (3.6–24.6) | 6.3 (2.5–18.7) |
| 5.0 (3.5–8.1) | 7.2 (6.0–26.0) | 5.1 (3.1–12.9) | 4.3 (2.3–8.2) | |
| Turning cards | 4.5 (5.0–9.2) | 11.0 (5.3–44.4) | 6.6 (4.1–31.1) | 4.4 (2.5–13.2) |
| 4.8 (3.1–10.7) | 6.5 (3.3–15.1) | 4.5 (3.8–9.2) | 4.3 (2.7–7.3) | |
| Lifting light objects | 4.1 (3.0–5.2) | 7.4 (5.4–31.7) | 5.4 (2.4–17.1) | 4.3 (2.6–10.2) |
| 4.2 (3.2–5.3) | 5.0 (2.9–8.9) | 3.9 (2.5–7.8) | 3.4 (2.5–5.6) | |
| Lifting heavy objects | 4.0 (2.6–6.4) | 7.8 (5.4–49.9) | 5.0 (2.4–14.8) | 4.2 (2.1–7.5) |
| 4.1 (2.9–6.8) | 5.1 (2.7–10.4) | 3.7 (2.5–6.2) | 3.5 (2.5–5.9) | |
| Sum | 22.3 (18.9–28.6) | 57.9 (23.1–240.6) | 35.2 (16.6–130.7) | 26.9 (15.2–69.0) |
| 24.0 (19.1–30.7) | 31.6 (18.4–58.0) | 23.3 (15.7–43.6) | 21.6 (14.6–31.8) | |
| Hand dynamometry (kg)b | 36.4 (16.0–61.0) | 21.4 (0.0–51.0) | 32.4 (9.0–59.0) | 37.1 (10.0–67.0) |
| 35.3 (16.0–59.0) | 40.9 (16.0–63.0) | 43.0 (13.0–63.0) | 43.9 (16.0–67.0) | |
| Pressure perception (g/mm2)b | 8.0 (5.2–10.0) | 38.6 (7.7–178.0) | 19.5 (5.7–178.0) | 20.4 (6.8–155.3) |
| 7.8 (5.8–11.0) | 11.3 (5.2–39.8) | 10.5 (6.2–20.5) | 10.1 (5.0–18.8) | |
Values are mean (range) except were indicated
NIHSS National Institute of Health Stroke Scale (“Cognitive Function” is the sum of aphasia and neglect items), n.a. not applicable
aMedian (range)
bUpper row: values for contralesional hand of patients, right hand of controls, lower row: values for ipsilesional hand of patients, left hand of controls