Table 2.
Assessment of the change in sensitivity and specificity of acute kidney injury biomarkers using contemporaneous measurements in patients admitted with a diagnosis other than sepsis or pneumonia compared to single biomarkers in isolation
Biomarker | Sensitivity (%) | Specificity (%) |
---|---|---|
Cys-C alone (in Group 2) | 100 | 85.7 |
pNGAL alone (in Group 2) | 100 | 57.1 |
C + P (in Group 2) | 100 | 92.9 |
Cys-C alone (in Group 3) | 60 | 85.7 |
pNGAL alone (in Group 3) | 80 | 57.1 |
C + P (in Group 3) | 20 | 92.9 |
C + P, Contemporaneous abnormal cystatin C (Cys-C) and plasma human neutrophil gelatinase-associated lipocalin (pNGAL)
For definition of groups, see Fig. 1b and section A biomarker panel improves specificity for acute kidney injury (AKI)