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. 2015 Apr 15;30(10):1861–1871. doi: 10.1007/s00467-015-3089-3

Table 2.

Assessment of the change in sensitivity and specificity of acute kidney injury biomarkers using contemporaneous measurements in patients admitted with a diagnosis other than sepsis or pneumonia compared to single biomarkers in isolation

Biomarker Sensitivity (%) Specificity (%)
Cys-C alone (in Group 2) 100 85.7
pNGAL alone (in Group 2) 100 57.1
C + P (in Group 2) 100 92.9
Cys-C alone (in Group 3) 60 85.7
pNGAL alone (in Group 3) 80 57.1
C + P (in Group 3) 20 92.9

C + P, Contemporaneous abnormal cystatin C (Cys-C) and plasma human neutrophil gelatinase-associated lipocalin (pNGAL)

For definition of groups, see Fig. 1b and section A biomarker panel improves specificity for acute kidney injury (AKI)