Table 1.
Summarizing table of the described data.
| Parameter | Tissue | Alteration in anti-Ang-2 mice | Statistics | |
|---|---|---|---|---|
| Plaque burden | Plaque size | Brachiocephalic artery | ↓ | * |
| Collar model | = | n.s. | ||
| Aortic root | = | n.s. | ||
| Degree of stenosis | Brachiocephalic artery | ↓ | ** | |
| Plaque phenotype | Necrotic core | Brachiocephalic artery | Absent in fatty streak | – |
| Collar model | = | n.s. | ||
| Aortic root | = | n.s. | ||
| Plaque collagen | Brachiocephalic artery | = | n.s. | |
| Aortic root | = | n.s. | ||
| Plaque macrophages | Brachiocephalic artery | = | n.s. | |
| Aortic root | = | n.s. | ||
| Microvessel density | Brachiocephalic artery | = | n.s. | |
| Aortic root | = | n.s. | ||
| Systemic effects | Angiopoetin-2 | Plasma | ↑ | ** |
| Cholesterol | Plasma | = | n.s. | |
| Triglycerides | Plasma | ↓ | * | |
| Cardiac function | US of the heart | = | n.s. | |
| Carotid strain + shear stress | US of carotid artery | = | n.s. | |
| Body weight | Before sacrifice | = | n.s. |
US = ultra sound; n.s. = not significant.
*p < 0.05, **p < 0.01.