Table 1.
Condition | Day 0 | Day 1 | Day 7 | Day 14 | Day 28 |
CT none | 131.25 ± 3.14 | 130.50 ± 1.51 | 126.78 ± 4.86 | 112.42 ± 4.55 | 133.88 ± 13.66 |
CT + AV | 137.0 ± 5.86 | 123.33 ± 2.85 | 126.8 ± 2.2 | 128.40 ± 7.02 | 180.67 ± 52.21 |
CT + SV | 143.13 ± 1.75 | 128.50 ± 3.10 | 126.80 ± 2.22 | 128.40 ± 7.02 | 152.88 ± 18.46 |
CT + PV | 142.63 ± 5.79 | 127.13 ± 3.36 | 122.20 ± 4.79 | 120.80 ± 4.47 | 130.63 ± 4.06 |
Diabetic none | 133.65 ± 3.51 | 445.41 ± 24.11a | 490.45 ± 34.34a | 530.09 ± 26.65a | 517.76 ± 18.11a |
Diabetic + AV | 133.00 ± 3.30 | 473.82 ± 40.23a | 497.38 ± 47.68a | 485.38 ± 48.73a | 500.73 ± 32.65a |
Diabetic + SV | 133.75 ± 2.70 | 413.19 ± 21.22a | 473.69 ± 27.39a | 483.23 ± 39.90a | 498.94 ± 30.62a |
Diabetic + PV | 126.88 ± 2.08 | 430.44 ± 27.31a | 524.38 ± 19.92a | 564.85 ± 13.57a | 557.25 ± 12.92a |
P < 0.05 vs age-matched C. Values are means ± SEM. Rats were injected with STZ on day 0. Blood glucose for diabetic rats: n = average of 10 rats per group. AV: Atorvastatin; SV: Simvastatin; PV: Pravastatin; CT: Control; STZ: Streptozotocin.