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. 2015 Aug 26;5:13454. doi: 10.1038/srep13454

Table 3. Meta-analysis results.

Outcome Studies Groups (HS/ACDF) Overall effect
p-Value Heterogeneity
Effect estimate 95% CI I2(%) p-Value
Operation time 5 74/86 2.21 −11.25, 15.67 0.75 88 <0.00001
Blood loss 4 67/79 −27.80 −47.08, −8.52 0.005 55 0.09
Complications 5 74/86 −0.01 −0.09, 0.06 0.73 0 0.77
VAS
 Preoperative 2 32/32 −0.10 −0.85, 0.65 0.79 0 1.00
 Postoperative 24 months 2 32/32 −1.00 −2.46, 0.47 0.18 75 0.05
C2–C7 ROM
 Preoperative 4 67/79 0.51 −3.73, 4.74 0.81 0 0.99
 Postoperative 24 months 2 32/32 9.50 1.44, 15.40 0.002 0 0.92
Superior adjacent level ROM
 Preoperative 4 67/79 −0.46 −2.15, 1.23 0.60 0 0.58
 Postoperative 24 months 2 32/32 −5.24 −7.57, −2.92 <0.00001 54 0.14
Inferior adjacent level ROM
 Preoperative 4 67/79 −0.45 −1.78, 0.87 0.50 0 0.41
 Postoperative 24 months 2 32/32 −4.62 −7.28, −1.96 0.0007 0 0.59

HS: hybrid surgery, ACDF: anterior cervical discectomy and fusion, ROM: range of motion, CI: confidence interval.