Table 1. List of compounds screened for GLUT5 fructose transport inhibition.
Epigallocatechin gallate (10 mM) | Arbutin (20 mM) |
Astragalin (D1, 20 mM) | Astragalin 1 glucoside (20 mM) |
Rutin (D1, 20 mM) | Astragalin 2 glucoside (20 mM) |
Gallic acid (D1, 20 mM) | Astragalin 6 glucoside (20 mM) |
Naringin (5 mM) | Fructose oligosaccharides (20 mM) |
Naringenin (D1, 20 mM) | Megafructose oligosaccharides (10 mM) |
Catechin hydrate (D1, 20 mM) | Bitter mellon (10 mg/ml) |
Curcumin (D1, 20 mM) | Rice wine ethanol extraction (10 mg/ml) |
Korean herbal wine (Bekseju) ethanol extraction (10 mg/ml) | Korean herbal wine (Bekseju) water extraction (10 mg/ml) |
Dihydromyricetin (D1, 20 mM) | Stevioside (20 mM) |
Ampelopsin glucoside 1 (10 mM) | Cycloisooligosaccharide (10 mM) |
Epigallocatechin gallate glucoside 1 (10 mM) | Human milk oligosaccharide mixture (without lactose) (10 mg/ml) |
Quercetin (D1, 20 mM) | Maltose (20 mM) |
Pyrogallol (20 mM) | Maltotriose (20 mM) |
Pyrocatechol (20 mM) | Maltotetraose (20 mM) |
Chrysin (5 mM) | Maltopentaose (20 mM) |
Hydroquinone (5 mM) | Maltohexaose (20 mM) |
Ascorbic acid (20 mM) | Rubusoside (20 mM) |
In parenthesis is the maximum concentration used for each compound. D1 indicates that the compound was dissolved in DMSO, at a final stock concentration of 500 mM, then diluted at the indicated concentration in the assay solution. Only astragalin-6-glucoside and rubusoside inhibited GLUT5 (in bold).