Expression of the CaSR and markers of neoplastic transformation in colorectal tumors. Tumor samples (mainly grade 2) and adjacent mucosa from 54 CRC patients were investigated for gene expression of the CaSR, the proliferation markers CDC6, CDT1, MCM2, MCM4, MCM6, MCM7, and CDC45, the differentiation marker SI and the pro-apoptotic marker BAX. Median, interquartile range and whiskers representing 5th to 95th percentile are shown. Statistical significance was calculated using paired t-tests. ***p < 0.001.